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Twice
in 1997, Steven Safe published opinion
pieces arguing that health risks of endocrine disruptors are
unlikely to be significant. The first of these was in the Wall Street
Journal (20 August 1997), the second in the New England Journal
of Medicine (30
0ctober 1997).
Both
pieces suffer from fundamental flaws, notably illogical arguments
and a highly selective view of the evidence.
Safe
in the Wall Street Journal: The WSJ op-ed examines a series
of separate lines of inquiry into endocrine disruption, concludes
that the evidence for each of them is weak or contradictory at best,
therefore concern about endocrine disruption in general is unwarranted.
This argument is flawed for two reasons. First, the theory of endocrine
disruption has many more bases than those Safe dismisses. Even if
he were correct about these, significant health concerns would remain.
Second, his dismissal of the individual issues he discusses is premature
at best and reflects a highly biased view of existing science. More...
Safe
in the New England Journal of Medicine: The New England Journal
commentary by Safe sparked an embarrassing public
controversy because the Journal failed to disclose that Safe
had been the recipient of significant industry funding, raising
questions about his objectivity. This was covered prominently by
the Boston Globe. [This never became an issue with the Wall Street
Journal because one begins with the assumption that people writing
on the editorial page arrive with entrenched biases.]
That
controversy aside, the main argument advanced in Safe's New England
Journal op-ed is that weakly estrogenic contaminants do not cause
breast cancer. As clincher, he cites a paper occurring in the same
issue of NEJM as refuting that hypothesis.
Yet
in fact Safe misrepresents the implications of this new work.
The result is that he concludes something which cannot be concluded
on the basis of the evidence he presents. Not only is it illogical,
but it has been disproven subsequently by new data. More...
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